Growth Factors
Tyk
Tyk
JAK
JAK
c-Myc
CDK
Pim1
Bcl-2
Src
STAT
STAT
STAT
DNA
STAT
STAT
STAT
SOCS
STAT
p21
Ras
Rac
MLK
p38
JNK
ERK1/2
MKK1/2
Raf
PI3K
Akt
mTOR
Cytokine
ISRE/GAS
Cell Growth, Survival,Differentiation and Oncogenesis
Src InhibitorsDasatinibSaracatinibPP2Bosutinib
JNK InhibitorsSP600125JNK-IN-8TanzisertibJNK ActivitorAnisomycin
Pan-STAT InhibitorSH-4-54Selective STAT InhibitorsFludarabine (STAT1)Stattic (STAT3)C188-9 (STAT3)AS1517499 (STAT6)
Pan-STAT InhibitorSH-4-54Selective STAT InhibitorsFludarabine (STAT1)Stattic (STAT3)C188-9 (STAT3)AS1517499 (STAT6)
Pan-JAK InhibitorsRuxolitinibTofacitinibAZD1480MomelotinibSelective JAK InhibitorsFedratinib (JAK2)Itacitinib(JAK1)Decernotinib(JAK3)
Pan-JAK InhibitorsRuxolitinibTofacitinibAZD1480MomelotinibSelective JAK InhibitorsFedratinib (JAK2)Itacitinib(JAK1)Decernotinib(JAK3)
Pan-PI3K Inhibitors3-MethyladenineLY294002DactolisibWortmanninSelective PI3K InhibitorsAlpelisib (PI3Kα)TGX-221 (p110β)AS-252424 (PI3Kγ)Idelalisib (p110δ)
Pan-Akt InhibitorsMK-2206IpatasertibCapivasertibAkt ActivatorSC79Selective Akt InhibitorsA-674563 (AKT1)CCT128930 (AKT2)
Pan-CDK InhibitorsDinaciclibFlavopiridolRoscovitineSelective CDK InhibitorsPalbociclib (CDK4/6)abemaciclib (CDK4/6)Ro-3306 (CDK1)THZ1 (CDK7)LDC000067 (CDK9)SNS-032 (CDK2)MSC2530818 (CDK8)
Pim InhibitorsPIM447AZD1208SGI-1776SMI-4a
c-Myc Inhibitors10058-F410074-G5
Pan-Bcl-2 InhibitorsNavitoclaxABT-737Selective Bcl-2 InhibitorsVenetoclax (Bcl-2)S63845 (MCL-1)A-1331852 (BCL-XL)
Tyk2 InhibitorPF-06700841
Tyk2 InhibitorPF-06700841
mTOR InhibitorsRapamycinEverolimusAZD8055Torin 1SapanisertibmTOR Agonist3BDO