PI3K
Akt
MEKK3
PKC8
PI3K
IKKα
IKKα
IKKβ
PKCβ
PKCζ
IKKα/β
GSK-3β
IκBα
NF-κB2P50/52
NF-κB2P52
NF-κB2P52
NF-κB2P50
NF-κB2p100
HDAC
ATM
NF-κB2p100
NF-κB2p100
IKKγNEMO
p38 MAPK
TNF
RIP
NIK
RIPK1
TRADD
PLC γ2
PLC γ2
MSK1
RelB
RelB
RelB
PKR
P65/RelA
P65/RelA
Growth Factors
Ag-MHC
Ag
LT, CD40L, BAFF/BLys
Inflammation
Immune Regulation
Survival
Proliferation
Lymphogenesis
B Cell Maturation
P65/RelA
UV
Pan-IκB/IKK InhibitorsBardoxolone MethylIKK-16Selective IκB/IKK InhibitorsMRT67307 (IKKϵ)IMD 0354 (IKKβ)TPCA-1 (IKK-2)
TNF-alpha InhibitorsPomalidomideLenalidomide
Pan-HDAC InhibitorsVorinostatPanobinostatTrichostatin ABelinostatSelective HDAC InhibitorsRGFP966 (HDAC3)Tubastatin A (HDAC6)PCI-34051 (HDAC8)
NF-κB InhibitorsBAY 11-7082JSH-23QNZSC75741Pyrrolidinedithiocarbamate
P
Growth Factors
Inflammation
Immune Regulation
Survival
Proliferation
Lymphogenesis B Cell Maturation
UV
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LT, CD40L,
BAFF/BLys
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Notes:
1:Clickable
2:Unclickable