1
Ca
2+
Ca
2+
NO
2
3
4
5
6
7
ER
PKD
SCK
TSAD
VAV2
Paxillin
IQGAP1
YES
SHB
NCK
PAK2
CDC42
HSP27
p85/PI3K
GAB1
BAD
eNOS
MK
PLCβ3
HSP27
DAG
Y801
Y951
VEGFA
VEGFC
VEGFD
VE-Cadherin
Y1054
Y1059
Y1175
Y1175
Y1214
Y1223
Y1305
Y1309
Y1319
FocalAdhesionTurnover
MembraneRuffles,Motility
Cell-cellContacts
SHCA
SOS
GRB2
PGI
2
Gene Transcription
Actin Polymerization,Stress Fiber Formation
Nucleus
Cell Proliferation
Cell Migration
Cell Vascular Development / Angiogensis
Cell Survival
Cell Permeability
PIP
2
PIP
2
IP
3
PIP
3
PLC-γ
Cross Talk with PlasmaMembrane-associatedHeterotrimeric G-protein
P
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Notes:
1:Clickable
2:Unclickable