S5734 |
Midodrine hydrochloride |
Midodrine hydrochloride is the hydrochloride salt form of midodrine, an adrenergic alpha-1 agonist used as a vasopressor. |
S8752 |
leniolisib (CDZ 173) |
Leniolisib (CDZ 173)是有效的选择性PI3Kδ抑制剂,对PI3Kα, PI3Kβ, PI3Kγ和PI3Kδ的IC50分别为0.244, 0.424, 2.23和0.011 μM。 |
S1435 |
Tamsulosin hydrochloride |
Tamsulosin (Flomax) hydrochloride是一种作用于前列腺的α1A肾上腺素拮抗剂。 |
S5901 |
Canagliflozin hemihydrate |
Canagliflozin hemihydrate是canagliflozin的半水化合物形式。Canagliflozin是SGLT2的抑制剂,对hSGLT2的IC50值为2.2 nM,对hSGLT2的选择性是对hSGLT1的413倍。 |
S1204 |
Melatonin |
Melatonin是一种 MT receptor 激动剂激素, 用作膳食补充品。Melatonin 是一种选择性的 ATF-6 的抑制剂并可下调 COX-2。Melatonin 可增强线粒体自噬并调节凋亡和自噬的稳态。 |
S8019 |
Capivasertib (AZD5363) |
Capivasertib (AZD5363)有效抑制Akt(Akt1/Akt2/3)的所有亚型,在无细胞试验中IC50为3 nM/8 nM/8 nM,对P70S6K/PKA也具有相似的抑制效果,而对ROCK1/2抑制活性较低。Phase 2。 |
S5695 |
Icatibant Acetate |
Icatibant Acetate(HOE-140 acetate)是bradykinin B2受体的拮抗剂,可用于治疗遗传性血管性水肿。 |
S5900 |
Edrophonium chloride |
Edrophonium chloride是edrophonium的氯盐形式。Edrophonium是一种快速起效、短效、易可逆的acetylcholinesterase (乙酰胆碱酯酶)抑制剂。 |
S5767 |
Aliskiren |
Aliskiren(CGP 60536)是一种renin (肾素)抑制剂,具有降压活性。 |
S5062 |
Daclatasvir Dihydrochloride |
Daclatasvir是一种具有口服活性的抗病毒剂,抑制HCV的NS5A区域,用于治疗慢性遗传型1和3类的HCV感染。 |
S5697 |
Isopropamide Iodide |
Isopropamide iodide is a long-acting quaternary anticholinergic drug used in the treatment of peptic ulcer and other gastrointestinal disorders. |
S5565 |
Triflupromazine hydrochloride |
Triflupromazine hydrochloride (Fluopromazine) is an antipsychotic medication of the phenothiazine class. |
S5491 |
Lomefloxacin |
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S5703 |
Carvedilol Phosphate |
Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity. |
S5721 |
Edetate calcium disodium |
Edetate (EDTA) calcium disodium is a chelating agent that is primarily used for the management of severe lead poisoning. |
S5397 |
Chlorhexidine |
Chlorhexidine is a disinfectant and topical anti-infective agent that is active against Gram-positive and Gram-negative organisms, facultative anaerobes, aerobes, and yeasts. |
S5693 |
Levomilnacipran Hydrochloride |
Levomilnacipran Hydrochloride is a selective serotonin and norepinephrine reuptake inhibitor with antidepressant activity. |
S5713 |
Pravastatin |
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S5715 |
Atorvastatin |
Atorvastatin 是一种降脂剂。 它是 hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase 的竞争性抑制剂,它可通过甲羟戊酸途径生物合成胆固醇的速率决定酶并激活自噬。 |
S5723 |
Carvedilol EP IMpurity E |
Carvedilol EP IMpurity E (Carvedilol USP E, Carvedilol Impurity E) is a nonselective beta blocker/alpha-1 blocker and used in management of congestive heart failure (CHF). |